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Randomized Controlled Trial
. 2009 Nov;99(11):2079-86.
doi: 10.2105/AJPH.2008.154476. Epub 2009 Sep 17.

Pregnancy as a window of opportunity for HIV prevention: effects of an HIV intervention delivered within prenatal care

Trace S Kershaw  1 , Urania Magriples, Claire Westdahl, Sharon Schindler Rising, Jeannette Ickovics
Affiliations
Randomized Controlled Trial

Pregnancy as a window of opportunity for HIV prevention: effects of an HIV intervention delivered within prenatal care

Trace S Kershaw et al. Am J Public Health. 2009 Nov.

Abstract

Objectives: We sought to determine whether an HIV prevention program bundled with group prenatal care reduced sexually transmitted infection (STI) incidence, repeat pregnancy, sexual risk behavior, and psychosocial risks.

Methods: We conducted a randomized controlled trial at 2 prenatal clinics. We assigned pregnant women aged 14 to 25 years (N = 1047) to individual care, attention-matched group care, and group care with an integrated HIV component. We conducted structured interviews at baseline (second trimester), third trimester, and 6 and 12 months postpartum.

Results: Mean age of participants was 20.4 years; 80% were African American. According to intent-to-treat analyses, women assigned to the HIV-prevention group intervention were significantly less likely to have repeat pregnancy at 6 months postpartum than individual-care and attention-matched controls; they demonstrated increased condom use and decreased unprotected sexual intercourse compared with individual-care and attention-matched controls. Subanalyses showed that being in the HIV-prevention group reduced STI incidence among the subgroup of adolescents.

Conclusion: HIV prevention integrated with prenatal care resulted in reduced biological, behavioral, and psychosocial risks for HIV.

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Figures

FIGURE 1
FIGURE 1
CONSORT study description. Note. CP = CenteringPregnancy group prenatal care control group; CPP = CenteringPregnancy group prenatal care plus HIV prevention components; IC = standard individual prenatal care control group; STI = sexually transmitted infection.
FIGURE 2
FIGURE 2
Among young pregnant women at 2 public clinics, (a) condom use percentage by intervention condition and (b) occasions of unprotected sexual intercourse by intervention condition: Atlanta, GA, and New Haven, CT, September 2001–December 2004. Note. CP = CenteringPregnancy group prenatal care control group; CPP = CenteringPregnancy group prenatal care plus HIV prevention components; IC = standard individual prenatal care control group. Sample size was N = 1047.
FIGURE 3
FIGURE 3
Sexually transmitted infection (STI) incidence at 12 months postpartum among young pregnant women at 2 public clinics, by intervention condition and age group: Atlanta, GA, and New Haven, CT, September 2001–December 2004. Note. STI testing for chlamydia and gonorrhea only. CP = CenteringPregnancy group prenatal care control group; CPP = CenteringPregnancy group prenatal care plus HIV prevention components; IC = standard individual prenatal care control group; STI = sexually transmitted infection. Sample size was N = 1047.
See this image and copyright information in PMC

References

    1. National Institutes of Health Office AIDS Research Trans-NIH Plan for HIV-Related Research Bethesda, MD: National Institutes of Health; 2005
    1. Meade CS, Ickovics JR. Systematic review of sexual risk among pregnant and mothering teens in the USA: pregnancy as an opportunity for integrated prevention of STD and repeat pregnancy. Soc Sci Med 2005;60:661–678 - PubMed
    1. Koniak-Griffin D, Lesser J, Nyamathi A, Uman G, Stein JA, Cumberland WG. Project CHARM: an HIV prevention program for adolescent mothers. Fam Community Health 2003;26:94–107 - PubMed
    1. Hobfoll SE, Jackson AP, Lavin J, Britton PJ, Shepherd JB. Reducing inner-city women's AIDS risk activities: a study of single, pregnant women. Health Psychol 1994;13:397–403 - PubMed
    1. Kelly JA, Murphy DA, Washington CD, et al. The effects of HIV/AIDS intervention groups for high-risk women in urban clinics. Am J Public Health 1994;84:1918–1922 - PMC - PubMed

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