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. 2009 Oct 7;7(19):4017-20.
doi: 10.1039/b909760k. Epub 2009 Aug 10.

A colorimetric and fluorescent merocyanine-based probe for biological thiols

Shu-Ping Wang  1 , Wu-Jian Deng, Dan Sun, Min Yan, Hong Zheng, Jin-Gou Xu
Affiliations
Free article

A colorimetric and fluorescent merocyanine-based probe for biological thiols

Shu-Ping Wang et al. Org Biomol Chem. .
Free article

Abstract

A new "dual-mode" chromogenic and fluorescent turn-on probe (2) for the selective sensing of biological thiols is reported. In MeOH-H(2)O cosolvent at physiological pH 7.40 (MeOH-H(2)O = 3:7), biological thiols cleave the 2,4-dinitrobenzenesulfonyl group to release the chromo- and fluorophore merocyanine (3).

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