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Case Reports
. 2009 Sep 21;15(35):4444-5.
doi: 10.3748/wjg.15.4444.

Preliminary experience of helical tomotherapy for locally advanced pancreatic cancer

Cyrus Chargari  1 , Francois Campana, Philippe Beuzeboc, Sofia Zefkili, Youlia M Kirova
Affiliations
Case Reports

Preliminary experience of helical tomotherapy for locally advanced pancreatic cancer

Cyrus Chargari et al. World J Gastroenterol. .

Abstract

Radiotherapy for locally advanced pancreatic cancer is technically difficult and frequently associated with high-grade digestive toxicity. Helical tomotherapy (HT) is a new irradiation modality that combines megavoltage computed tomography imaging for patient positioning with intensity-modulated fan-beam radiotherapy. Its recent availability opens new fields of exploration for pancreatic radiotherapy as a result of its ability to tailor very well-defined dose distributions around the target volumes. Here, we report the use of HT in two patients with locally advanced pancreatic cancer. Doses to the bowel, kidneys and liver were reduced significantly, which allowed for excellent treatment tolerance without any high-grade adverse effects in either patient.

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Figures

Figure 1
Figure 1
Distribution of isodoses with HT treatment planning in patient 1 (A) and patient 2 (B), in axial and coronal representation. The different doses are represented with different colors. Red color represents the target volume dose.
See this image and copyright information in PMC

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