Performance of a new interference-resistant glucose meter

Abstract

Objectives: Glucose meters are widely used in self and hospital monitoring of blood glucose. We examined the analytical performance of a StatStrip glucose monitoring system.

Design and methods: Linearity, % recovery and within-run imprecision were studied using glucose-spiked whole blood. A total of 120 heparinized samples were used in method comparison using a plasma hexokinase on the Dimension RxL MAX analyzer as the comparison method. Common interferences were tested on the StatStrip, Accu-Chek Advantage and the MediSense Optium glucose meters at low, middle and high glucose levels.

Results: The StatStrip assay showed excellent linearity and recovery. The coefficient of variations for imprecision were <5%. This meter correlated well with the comparison method (y=0.994X+0.03; r=0.995, S(y/x)=0.05 mmol/L, bias=-0.01 mmol/L). Of the three meters tested, only the StatStrip showed interference <10% for all spiked levels of acetaminophen, ascorbic acid, maltose and hematocrit at three levels of glucose tested.

Conclusions: The StatStrip meter showed good performance and is suitable for point-of-care hospital glucose testing.