Domino palladium-catalyzed Heck-intermolecular direct arylation reactions
- PMID: 19772339
- DOI: 10.1021/ol901799p
Domino palladium-catalyzed Heck-intermolecular direct arylation reactions
Abstract
A domino palladium-catalyzed Heck-intermolecular direct arylation reaction has been developed, giving access to a variety of dihydrobenzofurans, indolines, and oxindoles. A variety of sulfur-containing heterocycles such as thiazoles, thiophenes, and benzothiophene can be employed as the direct arylation coupling partner in yields up to 99%.
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