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. 2009 Oct 15;11(20):4560-3.
doi: 10.1021/ol901799p.

Domino palladium-catalyzed Heck-intermolecular direct arylation reactions

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Domino palladium-catalyzed Heck-intermolecular direct arylation reactions

Olivier René et al. Org Lett. .

Abstract

A domino palladium-catalyzed Heck-intermolecular direct arylation reaction has been developed, giving access to a variety of dihydrobenzofurans, indolines, and oxindoles. A variety of sulfur-containing heterocycles such as thiazoles, thiophenes, and benzothiophene can be employed as the direct arylation coupling partner in yields up to 99%.

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