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. 1977 Jul 15;39(1):43-51.
doi: 10.1007/BF00690384.

An adult case of canine neuronal ceroid-lipofuscinosis

J F Cummings, A de Lahunta

An adult case of canine neuronal ceroid-lipofuscinosis

J F Cummings et al. Acta Neuropathol. .

Abstract

Intraneuronal accumulation of cytosomes with the fluorescent and tinctorial properties of ceroidlipofuscin occurred in the C.N.S. of a fully matured dog with signs of slowly progressive cerebellar disease. Ultrastructural study revealed various membrane-bound inclusions in addition to typical lipofuscin granules. The clinicopathologic findings in this case were contrasted with those occurring in English Setters with juvenile neuronal ceroid-lipofuscinosis, and compared with those reported in Kufs' disease in man.

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