MicroRNAs in memory processing
- PMID: 19778498
- DOI: 10.1016/j.neuron.2009.09.007
MicroRNAs in memory processing
Abstract
MicroRNAs are a class of small RNA molecules that regulate the expression of a wide variety of genes. In this issue of Neuron, Rajasethupathy and colleagues identify 170 distinct microRNAs in Aplysia, including one, miR-124, that plays a critical role in the regulation of signaling molecules underlying synaptic plasticity and memory.
Comment on
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Characterization of small RNAs in Aplysia reveals a role for miR-124 in constraining synaptic plasticity through CREB.Neuron. 2009 Sep 24;63(6):803-17. doi: 10.1016/j.neuron.2009.05.029. Neuron. 2009. PMID: 19778509 Free PMC article.
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