Independent genetic determinants of pancreatic and pulmonary status in cystic fibrosis
- PMID: 1977977
- DOI: 10.1016/0140-6736(90)92566-z
Independent genetic determinants of pancreatic and pulmonary status in cystic fibrosis
Abstract
The concordance of pancreatic and pulmonary status among siblings with cystic fibrosis, the cystic fibrosis genotype, and non-genetic factors were analysed in adult patients with cystic fibrosis. Genetic factors were more important than non-genetic factors in affecting the severity of pancreatic and lung disease. The genetic factors were independent of each other and did not invariably cosegregate with specific mutations at the cystic fibrosis locus.
Comment in
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Determinants of pancreatic and pulmonary status of cystic fibrosis.Lancet. 1991 Jan 5;337(8732):54-5. doi: 10.1016/0140-6736(91)93376-k. Lancet. 1991. PMID: 1670677 No abstract available.
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Genotype/phenotype discrepancies in cystic fibrosis.Lancet. 1991 Jan 12;337(8733):121. doi: 10.1016/0140-6736(91)90786-o. Lancet. 1991. PMID: 1670713 No abstract available.
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Genetic determinants in cystic fibrosis.Lancet. 1991 Mar 9;337(8741):623. doi: 10.1016/0140-6736(91)91697-s. Lancet. 1991. PMID: 1671984 No abstract available.
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