Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 1990 Nov 3;336(8723):1081-4.
doi: 10.1016/0140-6736(90)92566-z.

Independent genetic determinants of pancreatic and pulmonary status in cystic fibrosis

G Santis  1 , L Osborne, R A Knight, M E Hodson
Affiliations

Independent genetic determinants of pancreatic and pulmonary status in cystic fibrosis

G Santis et al. Lancet. .

Abstract

The concordance of pancreatic and pulmonary status among siblings with cystic fibrosis, the cystic fibrosis genotype, and non-genetic factors were analysed in adult patients with cystic fibrosis. Genetic factors were more important than non-genetic factors in affecting the severity of pancreatic and lung disease. The genetic factors were independent of each other and did not invariably cosegregate with specific mutations at the cystic fibrosis locus.

PubMed Disclaimer

Comment in

Publication types

MeSH terms

LinkOut - more resources