Linking the cell cycle to histone modifications: Dot1, G1/S, and cycling K79me2
- PMID: 19782019
- DOI: 10.1016/j.molcel.2009.09.010
Linking the cell cycle to histone modifications: Dot1, G1/S, and cycling K79me2
Abstract
In a recent issue of Molecular Cell, Schulze et al. (2009) described distinct distributions and regulation of Dot1-dependent methylation states at lysine 79 on histone H3 and showed cell-cycle regulation of K79 dimethylation on genes expressed during the G1/S phase.
Comment on
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Linking cell cycle to histone modifications: SBF and H2B monoubiquitination machinery and cell-cycle regulation of H3K79 dimethylation.Mol Cell. 2009 Sep 11;35(5):626-41. doi: 10.1016/j.molcel.2009.07.017. Epub 2009 Aug 13. Mol Cell. 2009. PMID: 19682934 Free PMC article.
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