Application of counterimmunoelectrophoresis in rapid detection of cytomegalovirus antibodies
- PMID: 197846
- DOI: 10.1093/ajcp/68.3.343
Application of counterimmunoelectrophoresis in rapid detection of cytomegalovirus antibodies
Abstract
Determination of cytomegalovirus antibodies by counterimmune-electrophoresis correlated well with results of complement-fixation antibody studies. The sensitivity and specificity of the counterimmunoelectrophoresis method (vs. complement fixation) was 88.9%. Fourfold antibody increases detected by complement fixation were also detected by counterimmunoelectrophoresis. In addition, no cross-reaction was observed in the counterimmunoelectrophoresis assay between other DNA viral antisera and cytomegalovirus antigen (Ad-169).
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