Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 1990;102(3):291-4.
doi: 10.1007/BF02244092.

Unaltered [3H]GBR-12935 binding after chronic treatment with dopamine active drugs

P Allard  1 , K Eriksson, S B Ross, J O Marcusson
Affiliations

Unaltered [3H]GBR-12935 binding after chronic treatment with dopamine active drugs

P Allard et al. Psychopharmacology (Berl). 1990.

Abstract

Rats were injected intraperitoneally with haloperidol 0.5 mg/kg, raclopride 1 mg/kg, bromocriptine 2.5 mg/kg, d-amphetamine 2.5 mg/kg, or cocaine 10 mg/kg twice daily for 21 days. The animals were sacrificed 72 h after last injection. Control rats were injected with saline, following the same schedule. The radioligand [3H]GBR-12935 was used as a presynaptic marker for dopamine neurites. There were no significant differences in [3H]GBR-12935 binding to striatum between drug-treated rats and controls.

PubMed Disclaimer

References

    1. Eur J Pharmacol. 1988 Nov 8;156(3):331-40 - PubMed
    1. J Neurochem. 1983 Jul;41(1):172-8 - PubMed
    1. Brain Res. 1985 Jul 15;338(2):243-8 - PubMed
    1. Eur J Pharmacol. 1986 Oct 7;129(3):401-4 - PubMed
    1. J Neurochem. 1987 Jun;48(6):1887-96 - PubMed

Publication types

LinkOut - more resources