An ancient disorder under iron control

M Metzler¹

Affiliations

¹ Department of Medical Genetics, Centre for Molecular Medicine and Therapeutics, Child and Family Research Institute, Vancouver, BC, Canada. martina@cmmt.ubc.ca

Comment

M Metzler. Clin Genet. 2009 Oct.

. 2009 Oct;76(4):341-3.

doi: 10.1111/j.1399-0004.2009.01260_1.x.

M Metzler¹

¹ Department of Medical Genetics, Centre for Molecular Medicine and Therapeutics, Child and Family Research Institute, Vancouver, BC, Canada. martina@cmmt.ubc.ca

No abstract available

Comment on

BMP6 is a key endogenous regulator of hepcidin expression and iron metabolism.
Andriopoulos B Jr, Corradini E, Xia Y, Faasse SA, Chen S, Grgurevic L, Knutson MD, Pietrangelo A, Vukicevic S, Lin HY, Babitt JL. Andriopoulos B Jr, et al. Nat Genet. 2009 Apr;41(4):482-7. doi: 10.1038/ng.335. Epub 2009 Mar 1. Nat Genet. 2009. PMID: 19252486 Free PMC article.
Lack of the bone morphogenetic protein BMP6 induces massive iron overload.
Meynard D, Kautz L, Darnaud V, Canonne-Hergaux F, Coppin H, Roth MP. Meynard D, et al. Nat Genet. 2009 Apr;41(4):478-81. doi: 10.1038/ng.320. Epub 2009 Mar 1. Nat Genet. 2009. PMID: 19252488