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Case Reports
. 1990 Dec;336(8730):1535-7.
doi: 10.1016/0140-6736(90)93309-d.

Quinine-induced disseminated intravascular coagulation

R L Spearing  1 , C M Hickton, P Sizeland, A Hannah, R R Bailey
Affiliations
Case Reports

Quinine-induced disseminated intravascular coagulation

R L Spearing et al. Lancet. 1990 Dec.

Abstract

Recurrent disseminated intravascular coagulation occurred in 3 women after ingestion of quinine tablets for cramp. All had circulating quinine-dependent antibodies to platelets and in 2 there was initial evidence of antibody consumption, with low titres that rose steeply over the next few days and remained high for many months.

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