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Controlled Clinical Trial
. 2009 Oct;24(5):795-9.
doi: 10.3346/jkms.2009.24.5.795. Epub 2009 Sep 23.

The effects of short-duration exercise on arterial stiffness in patients with stable coronary artery disease

Jidong Sung  1 , Jeong Hoon Yang, Soo Jin Cho, Sun Hee Hong, Eun Hee Huh, Seung Woo Park
Affiliations
Controlled Clinical Trial

The effects of short-duration exercise on arterial stiffness in patients with stable coronary artery disease

Jidong Sung et al. J Korean Med Sci. 2009 Oct.

Abstract

Arterial stiffness is an important contributor to the development of cardiovascular disease. We investigated the effect of short duration exercise using the treadmill test on arterial stiffness in the presence of coronary artery disease. We enrolled patients with and without coronary artery diseases (CAD and control group, 50 patients each) referred for treadmill testing. Brachial-ankle pulse wave velocity (baPWV) were measured before and after treadmill testing. Values of baPWV were significantly reduced at 10 min after exercise in both groups, more in the CAD group than in the control group (baseline baPWV and post-exercise change [cm/sec]: 1,527+/-245 and -132+/-155 in the CAD group, 1,439+/-202 and -77+/-93 in the control group, respectively, P for change in each group <0.001, P for difference in changes between the two groups <0.001). These findings persisted after adjusting for age, body mass index, systolic blood pressure, mean arterial pressure (MAP), MAP decreases, and baseline baPWV. Significant post-exercise baPWV reductions were observed in both groups, and more prominently in the CAD group. This finding suggests that short-duration exercise may effectively improve arterial stiffness even in patients with stable coronary artery disease.

Keywords: Brachial Artery; Coronary Artery Disease; Exercise.

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References

    1. Sugawara J, Otsuki T, Tanabe T, Maeda S, Kuno S, Ajisaka R, Matsuda M. The effects of low-intensity single-leg exercise on regional arterial stiffness. Jpn J Physiol. 2003;53:239–241. - PubMed
    1. Arnett DK, Evans GW, Riley WA. Arterial stiffness: a new cardiovascular risk factor? Am J Epidemiol. 1994;140:669–682. - PubMed
    1. Sugawara J, Maeda S, Otsuki T, Tanabe T, Ajisaka R, Matsuda M. Effects of nitric oxide synthase inhibitor on decrease in peripheral arterial stiffness with acute low-intensity aerobic exercise. Am J Physiol Heart Circ Physiol. 2004;287:H2666–H2669. - PubMed
    1. Edwards DG, Schofield RS, Magyari PM, Nichols WW, Braith RW. Effect of exercise training on central aortic pressure wave reflection in coronary artery disease. Am J Hypertens. 2004;17:540–543. - PubMed
    1. Wada T, Kodaira K, Fujishiro K, Maie K, Tsukiyama E, Fukumoto T, Uchida T, Yamazaki S. Correlation of ultrasound-measured common carotid artery stiffness with pathological findings. Arterioscler Thromb. 1994;14:479–482. - PubMed

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