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. 2010 Feb;18(2):181-6.
doi: 10.1007/s00167-009-0921-y. Epub 2009 Oct 1.

Prophylactic use of antibiotic-loaded bone cement in primary total knee replacement

Pietro Randelli  1 , Francesco R Evola, Paolo Cabitza, Luca Polli, Matteo Denti, Luca Vaienti
Affiliations

Prophylactic use of antibiotic-loaded bone cement in primary total knee replacement

Pietro Randelli et al. Knee Surg Sports Traumatol Arthrosc. 2010 Feb.

Abstract

Despite significant advances in intraoperative antimicrobial procedures, deep infection remains the most devastating complication following total joint arthroplasty. Clinical studies' results and safety profile of antibiotic-loaded bone cement are discussed in this review. Antibiotic bone cement prophylaxis is a safe and effective strategy in reducing the risk of deep infection following primary total joint arthroplasty.

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