Successful treatment of isolated subglottic haemangioma with propranolol alone
- PMID: 19796830
- DOI: 10.1016/j.ijporl.2009.08.020
Successful treatment of isolated subglottic haemangioma with propranolol alone
Abstract
Subglottic haemangioma is a rare but potentially life threatening condition which requires intervention. Many different treatments have been described with varying degrees of success and complications. Recently, successful treatment with propranolol has been reported in 11 cases of cutaneous haemangiomas and then in two cases of subglottic haemangiomas with extensive cutaneous lesions in conjunction with other treatment modalities. We describe the successful treatment with propranolol, of a stridulous four-month-old child with a 95% obstructing subglottic haemangioma. This was achieved without the need for tracheostomy or any other surgical intervention, and with no reported side effects. We now believe the new discovery of a dramatic response to propranolol allows treatment in the acute setting and following further study may render surgical treatment of subglottic haemangioma obsolete.
Similar articles
-
Management of infantile subglottic hemangioma: acebutolol or propranolol?Int J Pediatr Otorhinolaryngol. 2010 Aug;74(8):959-61. doi: 10.1016/j.ijporl.2010.05.013. Epub 2010 Jun 16. Int J Pediatr Otorhinolaryngol. 2010. PMID: 20557953
-
Case report: Treatment failure using propanolol for treatment of focal subglottic hemangioma.Int J Pediatr Otorhinolaryngol. 2010 Aug;74(8):956-8. doi: 10.1016/j.ijporl.2010.05.012. Int J Pediatr Otorhinolaryngol. 2010. PMID: 20846505
-
Failure of propranolol in the treatment of childhood haemangiomas of the head and neck.J Laryngol Otol. 2011 Nov;125(11):1164-72. doi: 10.1017/S0022215111001538. Epub 2011 Aug 16. J Laryngol Otol. 2011. PMID: 21846414
-
A meta-analysis on the effectiveness of propranolol for the treatment of infantile airway haemangiomas.Int J Pediatr Otorhinolaryngol. 2011 Apr;75(4):455-60. doi: 10.1016/j.ijporl.2011.01.028. Epub 2011 Feb 17. Int J Pediatr Otorhinolaryngol. 2011. PMID: 21333364 Review.
-
Subglottic hemangioma.Otolaryngol Clin North Am. 2008 Oct;41(5):903-11, viii-ix. doi: 10.1016/j.otc.2008.04.009. Otolaryngol Clin North Am. 2008. PMID: 18775341 Review.
Cited by
-
The effectiveness of propranolol in treating infantile haemangiomas: a meta-analysis including 35 studies.Br J Clin Pharmacol. 2014 Jul;78(1):44-57. doi: 10.1111/bcp.12235. Br J Clin Pharmacol. 2014. PMID: 24033819 Free PMC article. Review.
-
Current perspectives on the optimal management of infantile hemangioma.Pediatric Health Med Ther. 2017 Dec 6;8:107-116. doi: 10.2147/PHMT.S115528. eCollection 2017. Pediatric Health Med Ther. 2017. PMID: 29388636 Free PMC article. Review.
-
Subglottic hemangioma treated with propranolol.Eplasty. 2014 Jan 15;14:ic2. eCollection 2014. Eplasty. 2014. PMID: 24501622 Free PMC article. No abstract available.
-
Propranolol treatment of subglottic hemangiomas: a review of the literature.Int J Clin Exp Med. 2015 Nov 15;8(11):19886-90. eCollection 2015. Int J Clin Exp Med. 2015. PMID: 26884900 Free PMC article. Review.
-
Stridor in asian infants: assessment and treatment.ISRN Otolaryngol. 2012 Feb 19;2012:915910. doi: 10.5402/2012/915910. Print 2012. ISRN Otolaryngol. 2012. PMID: 23724274 Free PMC article.
Publication types
MeSH terms
Substances
LinkOut - more resources
Full Text Sources
Medical