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Editorial
. 2009 Sep 25;105(7):611-3.
doi: 10.1161/CIRCRESAHA.109.206912.

Titin phosphorylation: myocardial passive stiffness regulated by the intracellular giant

S Hinan Ahmed, Merry L Lindsey
Editorial

Titin phosphorylation: myocardial passive stiffness regulated by the intracellular giant

S Hinan Ahmed et al. Circ Res. .
No abstract available

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Figures

Figure 1
Figure 1
Simplified schematic showing the putative mechanism of modulating cardiomyocyte stiffness in different cardiomyopathy disease states. Two distinct pathways involved are adrenergic stimulation directed domain specific titin phosphorylation and titin isoform switching. PKA: Protein kinase A, PKG: protein kinase G, PKCα: Protein kinase-C α isoform. For detailed domain names see nomenclature form.
See this image and copyright information in PMC

Comment on

References

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