[Regulation of phenylalanine biosynthesis in the obligate methylotroph Methylobacillus M75]
[Article in
Russian]
- PMID: 1979836
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[Regulation of phenylalanine biosynthesis in the obligate methylotroph Methylobacillus M75]
[Article in
Russian]
Mol Gen Mikrobiol Virusol.
1990 Oct.
Abstract
Regulation of phenylalanine biosynthesis has been studied in the bacterium Methylobacillus M75 on the level of enzymes 3-deoxy-D-arabinoheptulose-7-phosphate-synthase, chorismatmutase, prephenatdehyrataze. The DAHP-synthase is shown to be synthesized constitutively and its activity is inhibited by all aromatic aminoacids and antranilate. The synthesis of chorismatmutase and prephenatdehydratase is repressed by tyrosine, the activity of the latter enzyme, besides that, is inhibited by phenylalanine, the effect of which is decreased in the presence of tyrosine.
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