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. 2009;81(8):62-4.

[Efficacy and safety of cyclosporin A withdrawal in children long after kidney transplantation]

[Article in Russian]
M M Kaabak, N N Babenko, E A Molchanova, A K Zokoev, Zh I Kurakina, V A Goriaĭnov, M G Minina, R B Akhmetshin
  • PMID: 19799203

[Efficacy and safety of cyclosporin A withdrawal in children long after kidney transplantation]

[Article in Russian]
M M Kaabak et al. Ter Arkh. 2009.

Abstract

Aim: Evaluation of cyclosporine (CSA) withdrawal safety and efficacy in children late after kidney transplantation.

Material and methods: Graft and patient survival was analysed in 30 kidney recipients operated in the central children's hospital in 1991-1999. Fifteen of 30 patients came for follow-up to the Russian Research Center for Surgery where CsA was withdrawn 6.8 +/- 2.7 after transplantation. The other 15 children continued immunosuppression with CsA.

Results: Higher graft survival was observed in children in whom CsA was discontinued.

Conclusion: Discontinuation of cyclosporine late after kidney transplantation results in improvement of graft survival in most of the patients.

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