doi: 10.1007/BF00426491.
Morphine action in grouped and isolated rats and mice
- PMID: 19802
- DOI: 10.1007/BF00426491
Item in Clipboard
Morphine action in grouped and isolated rats and mice
Psychopharmacology (Berl).
.
Abstract
The present study determines the analgesic effects of morphine in grouped and isolated rats and mice. Isolated animals developed altered behavioral patterns, including mouse-killing in rats and mutual aggressiveness in mice. The analgesic effect of morphine was tested by tail compression in rats and by the hot plate for mice. Isolated rats developing mouse-killing behavior had a raised pain threshold, while indifferent animals (nonkillers) responded less to morphine. Isolated mice, particularly low aggressors, gave enhanced responses to morphine.
Similar articles
-
Factors which might modify analgesic effect of morphine in differentially housed rats.Pol J Pharmacol Pharm. 1977 Mar-Apr;29(2):117-21. Pol J Pharmacol Pharm. 1977. PMID: 16253
-
Morphine analgesia in grouped and isolated rats.Psychopharmacologia. 1975;41(1):11-4. doi: 10.1007/BF00421298. Psychopharmacologia. 1975. PMID: 1168352
-
Effect of apomorphine on the antinociceptive activity of morphine.Psychopharmacology (Berl). 1977 Jun 6;53(1):65-72. doi: 10.1007/BF00426695. Psychopharmacology (Berl). 1977. PMID: 18752
-
[Ritanserin prolongs the analgesic effect of morphine and slows the development of tolerance].Eksp Klin Farmakol. 1997 Mar-Apr;60(2):10-3. Eksp Klin Farmakol. 1997. PMID: 9206558 Russian.
-
Repeated neonatal maternal separation alters morphine-induced antinociception in male rats.Brain Res Bull. 2001 Apr;54(6):649-54. doi: 10.1016/s0361-9230(01)00485-3. Brain Res Bull. 2001. PMID: 11403991
Cited by
-
Isolation housing decreases the effectiveness of morphine in the conditioned taste aversion paradigm.Psychopharmacology (Berl). 1987;92(1):48-51. doi: 10.1007/BF00215478. Psychopharmacology (Berl). 1987. PMID: 3110828
-
Innovations and advances in modelling and measuring pain in animals.Nat Rev Neurosci. 2022 Feb;23(2):70-85. doi: 10.1038/s41583-021-00536-7. Epub 2021 Nov 26. Nat Rev Neurosci. 2022. PMID: 34837072 Free PMC article. Review.
-
Brief social isolation, pain responsiveness, and morphine analgesia in young rats.Psychopharmacology (Berl). 1980;72(1):111-2. doi: 10.1007/BF00433816. Psychopharmacology (Berl). 1980. PMID: 6781002
-
Socially induced morphine pseudosensitization in adolescent mice.Behav Pharmacol. 2010 Mar;21(2):112-20. doi: 10.1097/FBP.0b013e328337be25. Behav Pharmacol. 2010. PMID: 20215964 Free PMC article.
-
The effect of housing and gender on preference for morphine-sucrose solutions in rats.Psychopharmacology (Berl). 1979;66(1):87-91. doi: 10.1007/BF00431995. Psychopharmacology (Berl). 1979. PMID: 120547
References
MeSH terms
Substances
LinkOut - more resources
Full Text Sources
