[Phospholipid methylation and the synaptosomal uptake of mediator amino acids]
- PMID: 1980281
[Phospholipid methylation and the synaptosomal uptake of mediator amino acids]
Abstract
The decrease in neurotransmitter amino acid uptake was observed in rat brain synaptosomes incubated with S-adenosyl-L-methyl-methionine. The inhibitory effect of neurotransmitter as a consequence of methylation of synaptic membrane is more pronounced in stimulatory transmitter amino acids. The effect of phospholipids on amino acid uptake in rat brain synaptosomes decreases with age.
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