doi: 10.1016/0742-8413(90)90014-z.
Effect of cefatrizine and cephaloglycine on L-leucine absorption in rat jejunum
Affiliations
- PMID: 1980443
- DOI: 10.1016/0742-8413(90)90014-z
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Effect of cefatrizine and cephaloglycine on L-leucine absorption in rat jejunum
Comp Biochem Physiol C Comp Pharmacol Toxicol.
1990.
Abstract
1. The oral cephalosporins: cefatrizine and cephaloglycine inhibit the L-leucine absorption in vivo on rat jejunum. 2. This inhibition is dose and time dependent and the effect is irreversible. 3. These antibiotics have a systemic effect on L-leucine absorption. 4. The inhibition of these antibiotics affect only leucine transport, without affecting the diffusion. 5. Cefatrizine and cephaloglycine inhibit the basolateral (Na(+)-K+) ATPase activity in rat jejunum.
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