Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Review
. 2009 Nov;7(11):775-86.
doi: 10.1038/nrmicro2221. Epub 2009 Oct 6.

The trypanosome flagellar pocket

Mark C Field  1 , Mark Carrington
Affiliations
Review

The trypanosome flagellar pocket

Mark C Field et al. Nat Rev Microbiol. 2009 Nov.

Abstract

Trypanosomes are important disease agents and excellent models for the study of evolutionary cell biology. The trypanosome flagellar pocket is a small invagination of the plasma membrane where the flagellum exits the cytoplasm and participates in many cellular processes. It is the only site of exocytosis and endocytosis and part of a multiorganelle complex that is involved in cell polarity and cell division. Several flagellar pocket-associated proteins have been identified and found to contribute to trafficking and virulence. In this Review we discuss the contribution of the flagellar pocket to protein trafficking, immune evasion and other processes.

PubMed Disclaimer

References

    1. Eur J Biochem. 2000 Jun;267(11):3309-14 - PubMed
    1. Br J Pharmacol. 2007 Dec;152(8):1155-71 - PubMed
    1. BMC Genomics. 2006 Feb 22;7:32 - PubMed
    1. J Cell Sci. 2004 Mar 1;117(Pt 7):1105-15 - PubMed
    1. J Clin Invest. 2006 Oct;116(10):2739-47 - PubMed

Publication types

MeSH terms

Substances

LinkOut - more resources