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Review
. 2009 Oct 15;122(Pt 20):3589-94.
doi: 10.1242/jcs.051011.

mTOR signaling at a glance

Mathieu Laplante  1 , David M Sabatini
Affiliations
Review

mTOR signaling at a glance

Mathieu Laplante et al. J Cell Sci. .
No abstract available

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Figures

Figure 1
Figure 1
See this image and copyright information in PMC

References

    1. Arsham, A. M., Howell, J. J. and Simon, M. C. (2003). A novel hypoxia-inducible factor-independent hypoxic response regulating mammalian target of rapamycin and its targets. J. Biol. Chem. 278, 29655-29660. - PubMed
    1. Bentzinger, C. F., Romanino, K., Cloetta, D., Lin, S., Mascarenhas, J. B., Oliveri, F., Xia, J., Casanova, E., Costa, C. F., Brink, M. et al. (2008). Skeletal muscle-specific ablation of raptor, but not of rictor, causes metabolic changes and results in muscle dystrophy. Cell Metab. 8, 411-424. - PubMed
    1. Bernardi, R., Guernah, I., Jin, D., Grisendi, S., Alimonti, A., Teruya-Feldstein, J., Cordon-Cardo, C., Simon, M. C., Rafii, S. and Pandolfi, P. P. (2006). PML inhibits HIF-1alpha translation and neoangiogenesis through repression of mTOR. Nature 442, 779-785. - PubMed
    1. Brugarolas, J., Lei, K., Hurley, R. L., Manning, B. D., Reiling, J. H., Hafen, E., Witters, L. A., Ellisen, L. W. and Kaelin, W. G., Jr (2004). Regulation of mTOR function in response to hypoxia by REDD1 and the TSC1/TSC2 tumor suppressor complex. Genes Dev. 18, 2893-2904. - PMC - PubMed
    1. Calnan, D. R. and Brunet, A. (2008). The FoxO code. Oncogene 27, 2276-2288. - PubMed

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