Identification of an infectious laryngotracheitis virus equivalent to the herpes simplex virus type 2 major DNA binding protein (ICP8)
- PMID: 1981454
Identification of an infectious laryngotracheitis virus equivalent to the herpes simplex virus type 2 major DNA binding protein (ICP8)
Abstract
A region of homology between the genomic DNA of infectious laryngotracheitis virus (ILTV), an avian herpesvirus, and the region encoding the herpes simplex virus type 2 (HSV-2) major DNA binding protein (ICP8) has been detected by the use of nick translation and Southern blot analysis. Further, a monoclonal antibody directed against the HSV-2 ICP8 protein detected has antigenic cross-reaction with ILTV as demonstrated by indirect immunofluorescence.
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