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Review
. 2009 Nov 3;583(21):3377-87.
doi: 10.1016/j.febslet.2009.09.051. Epub 2009 Oct 5.

Deceptively simple but simply deceptive--Caenorhabditis elegans lifespan studies: considerations for aging and antioxidant effects

Jan Gruber  1 , Li Fang Ng, Suresh Kumar Poovathingal, Barry Halliwell
Affiliations
Free article
Review

Deceptively simple but simply deceptive--Caenorhabditis elegans lifespan studies: considerations for aging and antioxidant effects

Jan Gruber et al. FEBS Lett. .
Free article

Abstract

The nematode worm Caenorhabditis elegans (C. elegans) is increasingly popular as a model organism for aging studies as well as for testing antioxidants and other compounds for effects on longevity. However, results in the literature are sometimes confusing and contradictory. This review introduces C. elegans as a model organism, discusses aspects that make it attractive for aging and antioxidant research, and addresses some problems and potential artifacts.

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