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Review
. 2010 Jan;16(1 Suppl):S133-7.
doi: 10.1016/j.bbmt.2009.10.003. Epub 2009 Oct 9.

Immune reconstitution: how it should work, what's broken, and why it matters

Ronald E Gress  1 , Stephen G Emerson, William R Drobyski
Affiliations
Review

Immune reconstitution: how it should work, what's broken, and why it matters

Ronald E Gress et al. Biol Blood Marrow Transplant. 2010 Jan.
No abstract available

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Figures

Figure 1
Figure 1
Model representing the post transplant time course of CD4+ T cell recovery in a patient with a robust renewal of thymopoiesis. Thymic enlargement peaks at 12 months post transplant and is accompanied by an increasing number of CD45RA+CD62L+ naive and TREC-bearing cells in the second year. Recovery of TCR repertoire diversity in the memory subpopulations follows and is dependent upon recovery of adequate numbers of naive cells.
See this image and copyright information in PMC

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