Lacosamide: what can be expected from the next new antiepileptic drug?
- PMID: 19826503
- PMCID: PMC2759042
- DOI: 10.1111/j.1535-7511.2009.01317.x
Lacosamide: what can be expected from the next new antiepileptic drug?
Comment on
-
Adjunctive lacosamide for partial-onset seizures: Efficacy and safety results from a randomized controlled trial.Epilepsia. 2009 Mar;50(3):443-53. doi: 10.1111/j.1528-1167.2008.01951.x. Epub 2009 Jan 17. Epilepsia. 2009. PMID: 19183227 Clinical Trial.
References
-
- Errington AC, Stohr T, Heers C, Lees G. The investigational anticonvulsant lacosamide selectively enhances slow inactivation of voltage-gated sodium channels. Mol Pharmacol. 2008;73:157–169. - PubMed
-
- Beydoun A, D'Souza J, Hebert D, Doty P. Lacosamide: pharmacology, mechanisms of action and pooled efficacy and safety data in partial-onset seizures. Expert Rev Neurother. 2009;9:33–42. - PubMed
-
- Ben-Menachem E, Biton V, Jatuzis D, Abou-Khalil B, Doty P, Rudd GD. Efficacy and safety of oral lacosamide as adjunctive therapy in adults with partial-onset seizures. Epilepsia. 2007;48:1308–1317. - PubMed
-
- Chung SS, Sperling M, Biton V, Krauss G, Beaman M, Hebert D. Lacosamide: efficacy and safety as oral adjunctive treatment for partial-onset seizures. Epilepsia. 2007;48:321.
Publication types
LinkOut - more resources
Full Text Sources
