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. 2009 Sep;6(9):2426-35.
doi: 10.3390/ijerph6092426. Epub 2009 Sep 10.

Alcohol consumption and development of acute respiratory distress syndrome: a population-based study

Lokendra Thakur  1 , Marija Kojicic, Sweta J Thakur, Matthew S Pieper, Rahul Kashyap, Cesar A Trillo-Alvarez, Fernandez Javier, Rodrigo Cartin-Ceba, Ognjen Gajic
Affiliations

Alcohol consumption and development of acute respiratory distress syndrome: a population-based study

Lokendra Thakur et al. Int J Environ Res Public Health. 2009 Sep.

Abstract

This retrospective population-based study evaluated the effects of alcohol consumption on the development of acute respiratory distress syndrome (ARDS). Alcohol consumption was quantified based on patient and/or family provided information at the time of hospital admission. ARDS was defined according to American-European consensus conference (AECC). From 1,422 critically ill Olmsted county residents, 1,357 had information about alcohol use in their medical records, 77 (6%) of whom developed ARDS. A history of significant alcohol consumption (more than two drinks per day) was reported in 97 (7%) of patients. When adjusted for underlying ARDS risk factors (aspiration, chemotherapy, high-risk surgery, pancreatitis, sepsis, shock), smoking, cirrhosis and gender, history of significant alcohol consumption was associated with increased risk of ARDS development (odds ratio 2.9, 95% CI 1.3-6.2). This population-based study confirmed that excessive alcohol consumption is associated with higher risk of ARDS.

Keywords: ARDS; alcohol; population.

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Figures

Figure 1.
Figure 1.
Study outline.
Figure 2.
Figure 2.
Dose response relationship of alcohol consumption on the development of ARDS.
Figure 3.
Figure 3.
Frequency of ARDS according to alcohol and smoking history A-alcohol, S-smoking (p < 0.005 Chi Square test; no significant differences were found between A+S-and other subgroups).
See this image and copyright information in PMC

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