Stem cells: A fateful age gap
- PMID: 19829363
- PMCID: PMC3947842
- DOI: 10.1038/461891a
Stem cells: A fateful age gap
Abstract
When a stem cell divides, one sister cell differentiates and the other retains its stem-cell identity. Differences in the age of an organelle — the centriole — inherited at cell division may determine these differing fates.
Comment on
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Asymmetric centrosome inheritance maintains neural progenitors in the neocortex.Nature. 2009 Oct 15;461(7266):947-55. doi: 10.1038/nature08435. Nature. 2009. PMID: 19829375 Free PMC article.
References
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- Basto R, et al. Cell. 2006;125:1375–1386. - PubMed
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