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. 2009 Jul 6:3:7495.
doi: 10.4076/1752-1947-3-7495.

Brown tumor of the maxillary sinus in a patient with primary hyperparathyroidism: a case report

Efklidis Proimos, Theognosia S Chimona, Dimetrio Tamiolakis, Michalis G Tzanakakis, Chariton E Papadakis

Brown tumor of the maxillary sinus in a patient with primary hyperparathyroidism: a case report

Efklidis Proimos et al. J Med Case Rep. .

Abstract

Introduction: Brown tumors are rare focal giant-cell lesions that arise as a direct result of the effect of parathyroid hormone on bone tissue in some patients with hyperparathyroidism. Brown tumors can affect the mandible, maxilla, clavicle, ribs, and pelvic bones. Therefore, diagnosis requires a systemic investigation for lesion differentiation.

Case presentation: We present a 42-year-old Greek woman, with a rare case of brown tumor of the maxillary sinus due to primary hyperparathyroidism. Primary hyperparathyroidism is caused by a solitary adenoma in 80% of cases and by glandular hyperplasia in 20%.

Conclusions: Differential diagnosis is important for the right treatment choice. It should exclude other giant cell lesions that affect the maxillae.

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Figures

Figure 1
Figure 1
Axial computed tomography of the paranasal sinuses showing a round osteolytic lesion of the right maxillary sinus.
Figure 2
Figure 2
Coronal magnetic resonance imaging of the paranasal sinuses showing a round, bone-expanding lesion in the anterior part of the right maxillary sinus with invasion of the adjacent floor of the orbit, anterior ethmoids and nasal cavity.
Figure 3
Figure 3
Brown tumor. Bone lesion with multinucleated giant cells, mononuclear stromal cells, osteoblastic and osteoclastic areas and deposits of hemosiderin. Hematoxylin and eosin stain, ×100.
See this image and copyright information in PMC

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