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Review
. 2009 Dec;21(10):737-44.
doi: 10.1016/j.clon.2009.09.002. Epub 2009 Oct 14.

Radiation-induced xerostomia: pathophysiology, prevention and treatment

S A Bhide  1 , A B Miah, K J Harrington, K L Newbold, C M Nutting
Affiliations
Review

Radiation-induced xerostomia: pathophysiology, prevention and treatment

S A Bhide et al. Clin Oncol (R Coll Radiol). 2009 Dec.

Abstract

Radiation-induced xerostomia is highly prevalent among patients treated for head and neck cancers. Consequently, survivors experience associated long-term toxicities that may be grouped as xerostomia syndrome: dry mouth, sore throat, altered taste, dental decay, changes in voice quality and impaired chewing and swallowing function. We present a review of published studies describing and reporting xerostomia and discuss advances made in the prevention and treatment of this common toxicity.

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