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. 2009 Sep 15;19(17):R733-4.
doi: 10.1016/j.cub.2009.07.026.

DNA distress: just ring 9-1-1

Michael Kemp  1 , Aziz Sancar
Affiliations
Free article

DNA distress: just ring 9-1-1

Michael Kemp et al. Curr Biol. .
Free article

Abstract

The Rad9-Hus1-Rad1 checkpoint clamp (9-1-1) is a central player in the cellular response to DNA damage; three groups have determined the crystal structure of 9-1-1, providing new insight into its loading mechanism and association with DNA damage checkpoint and repair enzymes.

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