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. 2010 Apr;2(2):61-2.
doi: 10.1093/jmcb/mjp030. Epub 2009 Oct 14.

Shifting in balance between osteogenesis and adipogenesis substantially influences hematopoiesis

Ryohichi Sugimura  1 , Linheng Li
Affiliations

Shifting in balance between osteogenesis and adipogenesis substantially influences hematopoiesis

Ryohichi Sugimura et al. J Mol Cell Biol. 2010 Apr.

Abstract

Adipocytes have been viewed as a space-filler in bone marrow for a long time. However, a recent study (Naveiras et al., 2009. Nature 460, 259-263) shows that adipocytes are microenvironmental components that suppress hematopoiesis under homeostatic and especially stressed conditions.

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