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. 2009 Nov 27;23(18):2497-506.
doi: 10.1097/QAD.0b013e328330ed8a.

HIV serosorting as a harm reduction strategy: evidence from Seattle, Washington

Susan Cassels  1 , Timothy W Menza, Steven M Goodreau, Matthew R Golden
Affiliations

HIV serosorting as a harm reduction strategy: evidence from Seattle, Washington

Susan Cassels et al. AIDS. .

Abstract

Objective: We sought to estimate how serosorting may affect HIV prevalence and individual risk among men who have sex with men in Seattle, Washington, and how the results vary under different assumptions of HIV testing frequency, heterogeneity in sexual behavior, and condom use.

Methods: We developed a deterministic mathematical model of HIV transmission dynamics. Data from the 2003 random digit dial study of men who have sex with men conducted in Seattle, Washington (n = 400) are used to parameterize the model.

Results: Predicted population-level HIV prevalence as well as an individual's risk of HIV acquisition decreases when the odds of serosorting are increased in the mathematical model. In our model based on observed levels of serosorting, we predict an HIV prevalence of 16%. In contrast, if serosorting were eliminated in the population, we predict that HIV prevalence would increase to 24.5%. However, our findings depend on rates of condom use, mean anal sex contact rates, and HIV testing in the population.

Conclusion: Under realistic scenarios of sexual behavior and testing frequency for men who have sex with men in the United States, serosorting can be an effective harm reduction strategy.

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Conflict of interest statement

There are no conflicts of interest.

Figures

Figure 1
Figure 1
Flow chart of mathematical model
Figure 2
Figure 2
Equilibrium HIV prevalence for a variety of mean anal sex contact rates, with and without condom use in perceived seroconcordant contacts
Figure 3
Figure 3
Equilibrium HIV prevalence for various levels of condom use in perceived serodiscordant and perceived seroconcordant contacts.
Figure 4
Figure 4
Equilibrium HIV prevalence by testing frequency and type.
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