Revision of late periprosthetic infections of total hip endoprostheses: pros and cons of different concepts
- PMID: 19834595
- PMCID: PMC2755126
- DOI: 10.7150/ijms.6.287
Revision of late periprosthetic infections of total hip endoprostheses: pros and cons of different concepts
Abstract
Many concepts have been devised for the treatment of late periprosthetic infections of total hip prostheses. A two-stage revision with a temporary antibiotic-impregnated cement spacer and a cemented prosthesis appears to be the most preferred procedure although, in recent times, there seems to be a trend towards cementless implants and a shorter period of antibiotic treatment. Because of the differences in procedure, not only between studies but also within studies, it cannot be decided which period of parenteral antibiotic treatment and which spacer period is the most suitable. The fact that comparable rates of success can be achieved with different treatment regimens emphasises the importance of surgical removal of all foreign materials and the radical debridement of all infected and ischaemic tissues and the contribution of these crucial procedures to the successful treatment of late periprosthetic infections.
Keywords: hip endoprostheses; periprosthetic infections.
Conflict of interest statement
Conflict of interest: The author has no conflict of interest
Figures
Similar articles
-
Two-stage revision of prosthetic hip joint infections using antibiotic-loaded cement spacers: When is the best time to perform the second stage?Int Orthop. 2015 Sep;39(9):1731-6. doi: 10.1007/s00264-015-2751-5. Epub 2015 Apr 14. Int Orthop. 2015. PMID: 25870167
-
Two-stage hip revision arthroplasty for periprosthetic joint infection without the use of spacer or cemented implants.Int Orthop. 2019 Nov;43(11):2457-2466. doi: 10.1007/s00264-019-04297-y. Epub 2019 Jan 18. Int Orthop. 2019. PMID: 30659319
-
Six-week antibiotic therapy after one-stage replacement arthroplasty for hip and knee periprosthetic joint infection.Med Mal Infect. 2020 Oct;50(7):567-574. doi: 10.1016/j.medmal.2020.03.003. Epub 2020 Mar 26. Med Mal Infect. 2020. PMID: 32284220
-
Rationale for one stage exchange of infected hip replacement using uncemented implants and antibiotic impregnated bone graft.Int J Med Sci. 2009 Sep 4;6(5):247-52. doi: 10.7150/ijms.6.247. Int J Med Sci. 2009. PMID: 19834590 Free PMC article. Review.
-
Two-stage revision for periprosthetic joint infection in cemented total hip arthroplasty: an increased risk for failure?Arch Orthop Trauma Surg. 2023 Jul;143(7):4481-4490. doi: 10.1007/s00402-022-04671-3. Epub 2022 Nov 3. Arch Orthop Trauma Surg. 2023. PMID: 36323976 Free PMC article. Review.
Cited by
-
High diagnostic value of synovial biopsy in periprosthetic joint infection of the hip.Clin Orthop Relat Res. 2013 Mar;471(3):956-64. doi: 10.1007/s11999-012-2474-5. Epub 2012 Jul 18. Clin Orthop Relat Res. 2013. PMID: 22806261 Free PMC article.
-
Creating a dual articulating antibiotic spacer for management of an infected total femur prosthesis hemiarthroplasty.Arthroplast Today. 2019 Aug 13;5(4):482-485. doi: 10.1016/j.artd.2019.07.002. eCollection 2019 Dec. Arthroplast Today. 2019. PMID: 31886393 Free PMC article.
-
Sufficient release of antibiotic by a spacer 6 weeks after implantation in two-stage revision of infected hip prostheses.Clin Orthop Relat Res. 2011 Nov;469(11):3141-7. doi: 10.1007/s11999-011-1937-4. Epub 2011 Jun 16. Clin Orthop Relat Res. 2011. PMID: 21678099 Free PMC article.
-
MicroRNA expression analysis in peripheral blood and soft-tissue of patients with periprosthetic hip infection.Bone Jt Open. 2024 Jun 6;5(6):479-488. doi: 10.1302/2633-1462.56.BJO-2023-0172.R2. Bone Jt Open. 2024. PMID: 38839054 Free PMC article.
-
Preoperative Synovial Fluid Cultures, and Biopsy Cultures After Dry Tap Aspiration, Are Valuable in Diagnosing a Periprosthetic Joint Infection: A Retrospective Study.Microorganisms. 2025 Mar 1;13(3):562. doi: 10.3390/microorganisms13030562. Microorganisms. 2025. PMID: 40142454 Free PMC article.
References
-
- Garvin KL, Hanssen AD. Current concepts review: Infection after total hip arthroplasty. J Bone Joint Surg Am. 1995;77:1576–1588. - PubMed
-
- Fitzgerald Jr RH. Infected total hip arthroplasty: Diagnosis and treatment. J Am Acad Orthop Surg. 1995;3:249–262. - PubMed
-
- Cui Q, Mihalko WM, Shields JS, Ries M, Saleh HJ. Antibiotic-impregnated cement spacers for the treatment of infection associated with total hip or knee arthroplasty. J Bone Joints Surg Am. 2007;89:871–882. - PubMed
-
- Hanssen AD, Osmon DR. Evaluation of a staging system for infected hip arthroplasty. Clin Orthop Rel Res. 2002;403:16–22. - PubMed
-
- Steinbrink K. The case of revision arthroplasty using antibiotic-loaded acrylic cement. Clin Orthop Rel Res. 1990;261:19–22. - PubMed
Publication types
MeSH terms
Substances
LinkOut - more resources
Full Text Sources
Medical
Miscellaneous