[Pathophysiology and classification of adhesions]

Abstract

The central issue in the pathophysiology of adhesions is the shift of the dynamic balance between fibrinolysis and fibrinogenesis to the side of fibrinogenesis. Permanent adhesions with the most varied morphology are formed by invasion of the fibrin network by fibroblasts and fibroid organization. Their classification by four degrees of severity is based on histological and morphological criteria. This classification has been shown useful and practicable for the objective examination and evaluation of relaparotomies in connection with expert opinion reports and animal experiments on adhesion research.