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Review
. 2009 Dec;11(14-15):1206-18.
doi: 10.1016/j.micinf.2009.10.001. Epub 2009 Oct 14.

Chikungunya virus takes centre stage in virally induced arthritis: possible cellular and molecular mechanisms to pathogenesis

Marie Christine Jaffar-Bandjee  1 , Trina Das, Jean Jacques Hoarau, Pascale Krejbich Trotot, Mélanie Denizot, Anne Ribera, Pierre Roques, Philippe Gasque
Affiliations
Free article
Review

Chikungunya virus takes centre stage in virally induced arthritis: possible cellular and molecular mechanisms to pathogenesis

Marie Christine Jaffar-Bandjee et al. Microbes Infect. 2009 Dec.
Free article

Abstract

Chikungunya virus (CHIKV) causes an acute symptomatic illness with fever, skin rash (hypersensitivity vasculitis), incapacitating arthralgia which can evolve to chronic arthritis in elderly patients. Clinical observations from cohort studies have been corroborated with data from experimental infection in several mouse and non-human primate models as discussed herein.

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