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doi: 10.1016/j.cell.2009.09.027.
Eyeing up new Wnt pathway players
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- PMID: 19837026
- DOI: 10.1016/j.cell.2009.09.027
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Eyeing up new Wnt pathway players
Cell.
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Free article
Abstract
The Wnt signaling pathway controls cell fate decisions during animal development and the self-renewal and repair of adult tissues. In this issue, Ye et al. (2009) and Junge et al. (2009) reveal how an unusual Wnt receptor-ligand complex associated with a spectrum of retinal diseases instructs vascular development in the retina.
Comment on
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Norrin, frizzled-4, and Lrp5 signaling in endothelial cells controls a genetic program for retinal vascularization.Cell. 2009 Oct 16;139(2):285-98. doi: 10.1016/j.cell.2009.07.047. Cell. 2009. PMID: 19837032 Free PMC article.
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TSPAN12 regulates retinal vascular development by promoting Norrin- but not Wnt-induced FZD4/beta-catenin signaling.Cell. 2009 Oct 16;139(2):299-311. doi: 10.1016/j.cell.2009.07.048. Cell. 2009. PMID: 19837033
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