Activation of a novel medullary pathway elicits a vagal, cholinergic bronchoconstriction in guinea-pigs
- PMID: 1983733
- DOI: 10.1016/0952-0600(90)90010-g
Activation of a novel medullary pathway elicits a vagal, cholinergic bronchoconstriction in guinea-pigs
Abstract
Electrical stimulation of structures within the rostral region of the dorsal medulla of the guinea-pig activates a vagal cholinergic bronchoconstriction pathway and simultaneously activates a sympathetic inhibitory input. Removal of the latter by spinal section potentiated CNS-induced bronchospasm.
Similar articles
-
Possible roles of the peripheral vagal nerve in histamine-induced bronchoconstriction in guinea-pigs.Eur Respir J. 1991 Jul;4(7):860-6. Eur Respir J. 1991. PMID: 1683293
-
Ganglion-blocking agents enhance neurally mediated bronchoconstriction in the guinea-pig: possible role of sensory neuropeptides.Eur J Pharmacol. 1990 May 16;180(2-3):239-45. doi: 10.1016/0014-2999(90)90307-r. Eur J Pharmacol. 1990. PMID: 1973115
-
Ipratropium bromide potentiates bronchoconstriction induced by vagal nerve stimulation in the guinea-pig.Eur J Pharmacol. 1987 Jul 9;139(2):187-91. doi: 10.1016/0014-2999(87)90251-2. Eur J Pharmacol. 1987. PMID: 2958300
-
(R)-alpha-methylhistamine augments neural, cholinergic bronchospasm in guinea pigs by histamine H1 receptor activation.Eur J Pharmacol. 1992 Feb 18;211(3):421-6. doi: 10.1016/0014-2999(92)90401-o. Eur J Pharmacol. 1992. PMID: 1319915
-
Evidence that distinct neural pathways mediate parasympathetic contractions and relaxations of guinea-pig trachealis.J Physiol. 1993 Nov;471:25-40. doi: 10.1113/jphysiol.1993.sp019889. J Physiol. 1993. PMID: 7907144 Free PMC article.
Cited by
-
Bradykinin-induced airflow obstruction and airway plasma exudation: effects of drugs that inhibit acetylcholine, thromboxane A2 or leukotrienes.Br J Pharmacol. 1993 Oct;110(2):657-64. doi: 10.1111/j.1476-5381.1993.tb13862.x. Br J Pharmacol. 1993. PMID: 8242239 Free PMC article.
-
Inhibition of sympathetic hypertensive responses in the guinea-pig by prejunctional histamine H3-receptors.Br J Pharmacol. 1992 Oct;107(2):347-51. doi: 10.1111/j.1476-5381.1992.tb12749.x. Br J Pharmacol. 1992. PMID: 1330174 Free PMC article.
-
Pulmonary function survey in spinal cord injury: influences of smoking and level and completeness of injury.Lung. 1995;173(5):297-306. doi: 10.1007/BF00176893. Lung. 1995. PMID: 7564488
MeSH terms
Substances
LinkOut - more resources
Full Text Sources