Autophagy, apoptosis, and the influenza virus M2 protein
- PMID: 19837369
- DOI: 10.1016/j.chom.2009.09.009
Autophagy, apoptosis, and the influenza virus M2 protein
Abstract
Viral subversion and inhibition of host cell autophagy has been documented for several viruses. In this issue of Cell Host & Microbe,Gannagé et al. (2009) show that the influenza virus M2 integral membrane protein blocks autophagosome maturation, significantly affecting host cell apoptosis.
Comment on
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Matrix protein 2 of influenza A virus blocks autophagosome fusion with lysosomes.Cell Host Microbe. 2009 Oct 22;6(4):367-80. doi: 10.1016/j.chom.2009.09.005. Cell Host Microbe. 2009. PMID: 19837376 Free PMC article.
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