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Comparative Study
. 2010 Feb;31(3):309-17.
doi: 10.1093/eurheartj/ehp422. Epub 2009 Oct 15.

Atrial fibrillation and long-term prognosis in patients hospitalized for heart failure: results from heart failure survey in Israel (HFSIS)

Avraham Shotan  1 , Moshe Garty, David S Blondhein, Simcha R Meisel, Basil S Lewis, Michael Shochat, Ehud Grossman, Avi Porath, Valentina Boyko, Reuven Zimlichman, Abraham Caspi, Shmuel Gottlieb; HFSIS Steering Committee and Investigators
Affiliations
Comparative Study

Atrial fibrillation and long-term prognosis in patients hospitalized for heart failure: results from heart failure survey in Israel (HFSIS)

Avraham Shotan et al. Eur Heart J. 2010 Feb.

Abstract

Aims: Atrial fibrillation (AF) and heart failure (HF) commonly coexist, and each adversely affects the other. The aim of the study was to prospectively evaluate the impact of AF and its subtypes on management, and early and long-term outcome of hospitalized HF patients.

Methods and results: Data were prospectively collected on HF patients hospitalized in all public hospitals in Israel as part of a national survey (HFSIS). Atrial fibrillation patients were subdivided into intermittent and chronic AF subgroups. During March-April 2003, we enrolled 4102 HF patients, of whom 1360 (33.2%) had AF [600 (44.1%) intermittent, 562 (41.3%) chronic]. Patients with AF were older (76.9 +/- 10.5 vs. 71.7 +/- 12.6 years, P = 0.0001), males, with preserved LV systolic function. Crude mortality rates for AF patients were progressively and consistently higher during hospitalization and during the 4-year follow-up period, especially in the chronic AF group (P = 0.0001). After covariate adjustment, AF was associated with increased 1-year mortality [HR 1.19, 95% CI (1.03-1.36)].

Conclusion: AF was present in a third of hospitalized HF patients, and identified a population with increased mortality risk, largely due to co-morbidities.

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