TLR2 joins the interferon gang
- PMID: 19841644
- DOI: 10.1038/ni1109-1139
TLR2 joins the interferon gang
Abstract
The induction of type I interferon is a critical checkpoint in antiviral immunity. Toll-like receptor 2 can unexpectedly induce type I interferon in the subset of inflammatory monocytes during infection with vaccinia virus.
Comment on
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Toll-like receptor 2 on inflammatory monocytes induces type I interferon in response to viral but not bacterial ligands.Nat Immunol. 2009 Nov;10(11):1200-7. doi: 10.1038/ni.1792. Epub 2009 Oct 4. Nat Immunol. 2009. PMID: 19801985 Free PMC article.
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