CRISPI: a CRISPR interactive database
- PMID: 19846435
- PMCID: PMC2788928
- DOI: 10.1093/bioinformatics/btp586
CRISPI: a CRISPR interactive database
Abstract
Summary: The CRISPR genomic structures (Clustered Regularly Interspaced Short Palindromic Repeats) form a family of repeats that is largely present in archaea and frequent in bacteria. On the basis of a formal model of CRISPR using very few parameters, a systematic study of all their occurrences in all available genomes of Archaea and Bacteria has been carried out. This has resulted in a relational database, CRISPI, which also includes a complete repertory of associated CRISPR-associated genes (CAS). A user-friendly web interface with many graphical tools and functions allows users to extract results, find CRISPR in personal sequences or calculate sequence similarity with spacers.
Availability: CRISPI free access at http://crispi.genouest.org
Contact: croussea@irisa.fr; jnicolas@irisa.fr
References
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- Barrangou R, et al. CRISPR provides acquired resistance against viruses in prokaryotes. Science. 2007;315:1709–1712. - PubMed
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