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. 2009 Nov;6(4):177-86.
doi: 10.1007/s11904-009-0024-x.

Improving the self-report of HIV antiretroviral medication adherence: is the glass half full or half empty?

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Improving the self-report of HIV antiretroviral medication adherence: is the glass half full or half empty?

Ira B Wilson et al. Curr HIV/AIDS Rep. 2009 Nov.

Abstract

Self-reports are the most widely used method for measuring antiretroviral adherence. The association between self-reports and viral loads has been repeatedly demonstrated, but this association does not address how well self-reports measure actual medication-taking behaviors. Understanding adherence self-reports requires studying the science of memory and the reporting of behaviors. In the first section of this review, we discuss research in cognitive psychology that pertains to adherence self-reports, focusing primarily on studies that examine cognitive processes respondents use to answer survey questions. In the second section, we review recent articles examining the relationship between self-reports and objective measures of adherence, highlighting the strength of associations and key methodologic issues. We conclude with key questions for future research and methodologic recommendations.

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Conflict of interest statement

Disclosure

No potential conflicts of interest relevant to this article were reported.

References

    1. Gordis L. Conceptual and methodologic problems in measuring patient compliance. In: Haynes RB, Taylor DW, Sackett DL, editors. Compliance in Health Care. Baltimore, MD: The Johns Hopkins University Press; 1979. pp. 23–44.
    1. Rand CS, Weeks K. Measuring adherence with medication regimens in clinical care and research. In: Shumaker SA, Schron EB, Ockene JK, McBee WL, editors. The Handbook of Health Behavior Change. 2. New York: Springer Publishing Company, Inc; 1998. pp. 114–132.
    1. Rand CS. “I took the medicine like you told me, Doctor”: Self-reports of adherence with medical regimens. In: Stone AA, Turkkan JS, Bachrach CA, et al., editors. The Science of Self-Report: Implications for Research and Practice. 1. Mahwah, NJ: Lawrence Erlbaum Associates, Publishers; 2000. pp. 257–276.
    1. Lu M, Safren SA, Skolnik PR, et al. Optimal recall period and response task for self-reported HIV medication adherence. AIDS Behav. 2007;12:86–94. This article uses original data from 156 participants to compare adherence questions with different recall periods and demonstrates that questions using a 30-day recall period produce adherence estimates that are more similar to electronically monitored rates, compared with 3- and 7-day periods. They also found that asking respondents to rate their overall adherence was more accurate than asking about the frequency of medication-taking or the percent of time medications were taken correctly. - PubMed
    1. Deeks SG. Treatment of antiretroviral-drug-resistant HIV-1 infection. Lancet. 2003;362:2002–2011. - PubMed

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