Why do we want to know how factor XII levels are modulated?
- PMID: 19850327
- PMCID: PMC2826583
- DOI: 10.1016/j.thromres.2009.09.023
Why do we want to know how factor XII levels are modulated?
References
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- Kannemeier C, Shibamiya A, Nakazawa F, Trusheim H, Ruppert C, Markart P, Song Y, Tzima E, Kennerknecht E, Niepmann M, von Bruehl M-L, Sedding D, Massberg S, Gunther A, Engelmann B, Preissner KT. Extracellular RNS constitutes a natural procoagulant cofactor in blood coagulation. Proc Natl Acad Sci. 2007;104:6388–6393. - PMC - PubMed
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- Maas C, Govers-Riemslag JWP, Bouma B, Schiks B, Hazenberg BPC, Lokhorst HM, Hammarstrom P, ten Cate H, do Groot PG, Bouma BN, Gebbink MFBG. Misfolded proteins activate factor XII in humans, leading to kallikrein formation without initiating coagulation. J Clin Invest. 2008;118:3208–3218. - PMC - PubMed
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