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. 2009 Oct;17(4):435-7.
doi: 10.1016/j.devcel.2009.10.004.

More than a pipe dream: uncovering mechanisms of vascular lumen formation

Kevin S Nelson  1 , Greg J Beitel
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More than a pipe dream: uncovering mechanisms of vascular lumen formation

Kevin S Nelson et al. Dev Cell. 2009 Oct.
Free article

Abstract

An unresolved question in vasculogenesis is how mammalian endothelial cells make lumens in developing vessels. In this issue of Developmental Cell, Strilic et al. present a comprehensive analysis of murine arterial lumen formation that defines cellular and molecular events required for lumen morphogenesis and argues against a previous paradigm of lumen formation.

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