DEGseq: an R package for identifying differentially expressed genes from RNA-seq data
- PMID: 19855105
- DOI: 10.1093/bioinformatics/btp612
DEGseq: an R package for identifying differentially expressed genes from RNA-seq data
Abstract
Summary: High-throughput RNA sequencing (RNA-seq) is rapidly emerging as a major quantitative transcriptome profiling platform. Here, we present DEGseq, an R package to identify differentially expressed genes or isoforms for RNA-seq data from different samples. In this package, we integrated three existing methods, and introduced two novel methods based on MA-plot to detect and visualize gene expression difference.
Availability: The R package and a quick-start vignette is available at http://bioinfo.au.tsinghua.edu.cn/software/degseq
Similar articles
-
GFOLD: a generalized fold change for ranking differentially expressed genes from RNA-seq data.Bioinformatics. 2012 Nov 1;28(21):2782-8. doi: 10.1093/bioinformatics/bts515. Epub 2012 Aug 24. Bioinformatics. 2012. PMID: 22923299
-
Detecting differentially expressed genes by smoothing effect of gene length on variance estimation.J Bioinform Comput Biol. 2015 Dec;13(6):1542004. doi: 10.1142/S0219720015420044. Epub 2015 Oct 11. J Bioinform Comput Biol. 2015. PMID: 26608751
-
DegPack: a web package using a non-parametric and information theoretic algorithm to identify differentially expressed genes in multiclass RNA-seq samples.Methods. 2014 Oct 1;69(3):306-14. doi: 10.1016/j.ymeth.2014.06.004. Epub 2014 Jun 26. Methods. 2014. PMID: 24981074
-
Sequencing transcriptomes in toto.Integr Biol (Camb). 2011 May;3(5):522-8. doi: 10.1039/c0ib00062k. Epub 2011 Feb 4. Integr Biol (Camb). 2011. PMID: 21298135 Review.
-
Statistical detection of differentially expressed genes based on RNA-seq: from biological to phylogenetic replicates.Brief Bioinform. 2016 Mar;17(2):243-8. doi: 10.1093/bib/bbv035. Epub 2015 Jun 24. Brief Bioinform. 2016. PMID: 26108230 Review.
Cited by
-
Transcriptome Analysis Reveals Immune and Antioxidant Defense Mechanisms in the Eriocheir japonica sinensis after Exposure to Ammonia.Animals (Basel). 2024 Oct 16;14(20):2981. doi: 10.3390/ani14202981. Animals (Basel). 2024. PMID: 39457912 Free PMC article.
-
The small molecule ZY-214-4 may reduce the virulence of Staphylococcus aureus by inhibiting pigment production.BMC Microbiol. 2021 Feb 27;21(1):67. doi: 10.1186/s12866-021-02113-5. BMC Microbiol. 2021. PMID: 33639851 Free PMC article.
-
Bayesian Hierarchical Model for Differential Gene Expression Using RNA-seq Data.Stat Biosci. 2015 May 1;7(1):48-67. doi: 10.1007/s12561-013-9096-7. Stat Biosci. 2015. PMID: 26191087 Free PMC article.
-
Cracking of jujube fruits is associated with differential expression of metabolic genes.FEBS Open Bio. 2020 Sep;10(9):1765-1773. doi: 10.1002/2211-5463.12925. Epub 2020 Jul 29. FEBS Open Bio. 2020. PMID: 32619338 Free PMC article.
-
Profiling of MicroRNAs Involved in Mepiquat Chloride-Mediated Inhibition of Internode Elongation in Cotton (Gossypium hirsutum L.) Seedlings.Front Plant Sci. 2021 Feb 24;12:643213. doi: 10.3389/fpls.2021.643213. eCollection 2021. Front Plant Sci. 2021. PMID: 33719323 Free PMC article.
Publication types
MeSH terms
Substances
LinkOut - more resources
Full Text Sources
Other Literature Sources
Molecular Biology Databases