doi: 10.1093/jnci/59.4.1291.
Subcellular distribution of the tumor-specific transplantation antigen of simian virus 40-transformed cells
- PMID: 198559
- DOI: 10.1093/jnci/59.4.1291
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Subcellular distribution of the tumor-specific transplantation antigen of simian virus 40-transformed cells
J Natl Cancer Inst.
1977 Oct.
Abstract
TU-5, a simian virus 40 (SV40)-transformed cell line of BALB/c origin, expressed the SV40-specific T-antigen and a transplantation antigen (TSTA). Nuclei and plasma membranes were prepared from these cells and shown on the basis of the distribution of T-antigen and histocompatibility (H-2) antigens to be relatively free of cross contamination. Most of the TSTA, estimated by tumor rejection, was associated with the nuclear fraction.
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