Rapid aldosterone signaling and vascular reactivity: relax or don't do it
- PMID: 19858736
- PMCID: PMC2797578
- DOI: 10.1097/FJC.0b013e3181c37ddc
Rapid aldosterone signaling and vascular reactivity: relax or don't do it
Comment on
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Nitric oxide-mediated dilation of arterioles to intraluminal administration of aldosterone.J Cardiovasc Pharmacol. 2009 Dec;54(6):535-42. doi: 10.1097/FJC.0b013e3181bfb00d. J Cardiovasc Pharmacol. 2009. PMID: 19770672 Free PMC article.
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References
-
- Booth RE, Johnson JP, Stockand JD. Aldosterone. Adv Physiol Educ. 2002;26:8–20. - PubMed
-
- Pitt B, Remme W, Zannad F, Neaton J, Martinez F, Roniker B, Bittman R, Hurley S, Kleiman J, Gatlin M. Eplerenone, a selective aldosterone blocker, in patients with left ventricular dysfunction after myocardial infarction. N Engl J Med. 2003;348:1309–1321. - PubMed
-
- Pitt B, Zannad F, Remme WJ, Cody R, Castaigne A, Perez A, Palensky J, Wittes J. The effect of spironolactone on morbidity and mortality in patients with severe heart failure. Randomized Aldactone Evaluation Study Investigators. N Engl J Med. 1999;341:709–717. - PubMed
-
- Struthers AD. Impact of aldosterone on vascular pathophysiology. Congest Heart Fail. 2002;8:18–22. - PubMed
-
- Farquharson CA, Struthers AD. Spironolactone increases nitric oxide bioactivity, improves endothelial vasodilator dysfunction, and suppresses vascular angiotensin I/angiotensin II conversion in patients with chronic heart failure. Circulation. 2000;101:594–597. - PubMed
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